Acetaminophen (Tylenol) is a common over-the-counter medication used for pain relief and fever reduction. However, despite it being a common household medication, acetaminophen overdose is extremely dangerous and life-threatening.
Acetaminophen overdose is the most common cause of acute liver failure in the U.S. The use of more than 3-4 grams (3,000-4,000 milligrams, or 6-8 extra strength Tylenol) of acetaminophen per day can result in liver failure and death. Additionally, patients with active liver disease or who drink alcohol regularly with acetaminophen use are at increased risk of liver failure and death.
We provide a range of doses here because experts disagree on the safe maximum dose. The most often cited daily maximum is 4 grams (4,000 mg), but current recommendations from Tylenol brand producer of acetaminophen are a maximum of 3 grams (3,000 mg) per day. (See this link and this research paper.)
Doses discussed here are for adults only. Pediatric doses are calculated by weight.
Why are the other answers incorrect?
A) Acetaminophen is not dangerous, even in overdose
Acetaminophen overdose is life-threatening and can cause acute liver failure.
B) Acceptable amounts of acetaminophen use is up to 6 grams per day
This is incorrect! Use of more than 3-4 grams per day is considered dangerous.
C) Patients with active liver disease can use acetaminophen freely
Patients with active liver disease are at increased risk for acute liver failure with acetaminophen use.
D) Drinking alcohol regularly while using acetaminophen poses no risk
Alcohol use alongside acetaminophen use also increases the risk of acute liver failure.
Only your Duration Health provider can decide, based on your medical history and other factors, whether it is medically appropriate for you to receive prescriptions.
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Only your Duration Health provider can decide, based on your medical history and other factors, whether it is medically appropriate for you to receive prescriptions. We do not sell prefabricated bags of pharmaceuticals. Each Duration Health Med Kit that contains prescription medications is custom assembled, tailored to each individual patient's needs.
Duration Health is not a pharmacy, is not a nonprescription retailer, and does not sell medications directly. To be able to deliver a customized kit of medications, Duration Health has partnered with a third-party mail order pharmacy. You may request that any prescriptions be sent to an alternate pharmacy. Duration Health charges an administrative convenience fee for its services, but Duration Health does not sell prescription or over-the-counter ("OTC") drugs, mark-up the cost of prescription or OTC drugs, or retain any portion of the fees our affiliated pharmacy charges to you. Nor does Duration Health provide medical advice about or prescribe OTC medications. In states where Duration Health’s physician consultation services are not offered, Duration Health only offers OTC products and does not provide clients with access to obtain a physician consultation. Clients are free to purchase OTC medications of their choice as an OTC-only kit.
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