Trimethoprim-sulfamethoxazole (TMP-SMX, generic for Bactrim, and also abbreviated SMZ-TMP) is an antibiotic. It can be used to treat urinary tract infections and skin infections, and can be used to treat infections caused by MRSA (Methicillin-resistant S. aureus) bacteria.
TMP-SMX is known to cause birth defects and should not be used by pregnant women. TMP-SMX may cause your skin to be more sensitive to sunlight. Avoid the sun while taking this medication.
Avoid if allergic to sulfa drugs. TMP-SMX can cause rare but fatal reactions including life-threatening types of rash (Stevens-Johnson syndrome, toxic epidermal necrolysis), liver failure (fulminant hepatic necrosis), and life-threatening low blood counts (aplastic anemia and thrombocytopenia). TMP-SMX can cause severe diarrhea (including C. difficile diarrhea). Stop taking TMP-SMX at the first sign of any rash.
|Urinary tract infection||TMP-SMX 1 tab by mouth twice a day for 7 days|
|Skin infection||TMP-SMX 1 tab by mouth twice a day for 7 days|
Adult doses are shown, unless otherwise specified. Refer to weight-based dosing guidelines for pediatric patients.
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