Ondansetron (generic for Zofran) is an anti-nausea medication, and prevents nausea and vomiting. It's in a class of medications called 5-HT3 antagonists that work by tricking the nausea centers in the brain. Ondansetron can be used to treat the symptoms of nausea and vomiting from non-serious causes, such as food poisoning, as well as more serious causes.
Avoid if you have certain heart rhythm problems (such as long QT syndrome) or if you take certain antidepressant medications.
Recognize that if someone continues to have nausea and vomiting, especially with abdominal pain, there might be a serious underlying cause. (See Abdominal Pain section). Ondansetron can be dangerous in combination with certain antidepressant medications, including SSRIs, SNRIs, MAOIs, and others, because it can lead to serotonin syndrome. Ondansetron can cause changes in the heart's rhythm (QT prolongation) that could be fatal.
|Nausea and vomiting||ondansetron 4 mg dissolve in mouth once|
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