Atovaquone-proguanil (generic for Malarone) is used for malaria prophylaxis in areas with chloroquine-resistant Plasmodium falciparum, and can be used in most parts of the world where malaria occurs. Take it daily for 1-2 days before possible exposure to malaria, and continue daily for 7 days after leaving an exposed area.
Absorption of atovaquone may be reduced in patients with diarrhea or vomiting, so the medication may not work as well. Relapse of malaria may occur if atovaquone-proguanil is used when someone is infected with multiple species of malaria parasite.
Do not use this or any other oral medication to treat severe malaria, because patients who are severely ill with malaria must be treated with IV medications. This medication can cause liver failure, and some people have needed a liver transplant after using this medication prophylactically for prevention of malaria. Atovaquone-proguanil tablets are contraindicated in individuals with known hypersensitivity reactions or allergic reaction to the medication or any of its components. Atovaquone-proguanil tablets are contraindicated for prophylaxis of P. falciparum malaria in patients with severe renal impairment.
|Malaria prophylaxis||250 mg atovaquone and 100 mg proguanil hydrochloride, 1 tablet by mouth once daily, begin 1–2 days before travel to malarious areas, take daily at the same time each day while in the malarious area, and for 7 days after leaving such areas|
Adult doses are shown, unless otherwise specified. Refer to weight-based dosing guidelines for pediatric patients.
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Atovaquone-proguanil (generic for Malarone) is used for malaria prophylaxis in areas with chloroquine-resistant Plasmodium falciparum, and can be used in most parts of the world where malaria occurs. Take it daily for 1-2 days before possible exposure to malaria, and continue daily for 7 days after leaving an exposed area. Only your Duration Health provider can decide, based on your medical history and other factors, whether it is medically appropriate for you to receive prescriptions. We do not sell prefabricated bags of pharmaceuticals. Each Duration Health Med Kit that contains prescription medications is custom assembled, tailored to each individual patient's needs.
Duration Health is not a pharmacy, is not a nonprescription retailer, and does not sell medications directly. To be able to deliver a customized kit of medications, Duration Health has partnered with a third-party mail order pharmacy. You may request that any prescriptions be sent to an alternate pharmacy. Duration Health charges an administrative convenience fee for its services, but Duration Health does not sell prescription or over-the-counter ("OTC") drugs, mark-up the cost of prescription or OTC drugs, or retain any portion of the fees our affiliated pharmacy charges to you. Nor does Duration Health provide medical advice about or prescribe OTC medications. In states where Duration Health’s physician consultation services are not offered, Duration Health only offers OTC products and does not provide clients with access to obtain a physician consultation. Clients are free to purchase OTC medications of their choice as an OTC-only kit.
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