Duration Health — Field Guide: Trimethoprim-Sulfamethoxazole Pediatric

trimethoprim-sulfamethoxazole pediatric

trimethoprim-sulfamethoxazole pediatric

Generic for Bactrim Pediatric®
Generic for Bactrim Pediatric®
PediatricsMedication

Prescription only

Introduction

Trimethoprim-sulfamethoxazole (TMP-SMX, generic for Bactrim, and also abbreviated SMZ-TMP) is an antibiotic. It may be used to treat urinary tract or ear infections in pediatric patients. Other antibiotics are usually preferred as first-line treatment options. The suspension form of this medication contains sulfamethoxazole (SMX) 200 mg and trimethoprim (TMP) 40 mg together in each 5 mL liquid. Dosing is based on the trimethoprim (TMP) component.

When to avoid

Do not use if there is a history of allergy or hypersensitivity to sulfa drugs or TMP-SMX. Do not use with a history of liver or kidney disease. Do not use in patients less than 2 months of age.

When is it dangerous

Avoid if allergic to sulfa drugs. TMP-SMX can cause rare but fatal reactions including life-threatening types of rash (Stevens-Johnson syndrome, toxic epidermal necrolysis), liver failure (fulminant hepatic necrosis), and life-threatening low blood counts (aplastic anemia and thrombocytopenia). TMP-SMX can cause severe diarrhea (including C. difficile diarrhea). Stop taking TMP-SMX at the first sign of any rash.

When is it used

Infection (pediatric) TMP-SMX pediatric 4 mg TMP per kg by mouth every 12 hours for 7 days. Maximum 160 mg TMP per dose.

Pediatric dosages are weight-based. Refer to weight-based dosing guidelines.

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Trimethoprim-sulfamethoxazole (TMP-SMX, generic for Bactrim, and also abbreviated SMZ-TMP) is an antibiotic. It may be used to treat urinary tract or ear infections in pediatric patients. Other antibiotics are usually preferred as first-line treatment options. The suspension form of this medication contains sulfamethoxazole (SMX) 200 mg and trimethoprim (TMP) 40 mg together in each 5 mL liquid. Dosing is based on the trimethoprim (TMP) component. Only your Duration Health provider can decide, based on your medical history and other factors, whether it is medically appropriate for you to receive prescriptions. We do not sell prefabricated bags of pharmaceuticals. Each Duration Health Med Kit that contains prescription medications is custom assembled, tailored to each individual patient's needs.

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